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Those trials compared taking rimonabant (20 milligrams a day) against a placebo. 15 -- People who take the weight-loss drug rimonabant may face heightened risks for severe depression and anxiety, Danish researchers report. Rimonabant is not yet approved for use in the United States, where it is known as Zimulti. The undeclared active pharmaceutical ingredients in some of these products include sibutramine (a controlled substance), rimonabant ( a drug not approved for marketing in the United States), phenytoin ( an anti-seizure medication), and phenolphthalein (a solution used in chemical experiments and a suspected cancer causing agent). Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs Advisory Committee did not recommend approval of rimonabant (Zimulti / Accomplia) to the US FDA.
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